細胞名稱

人子宮內膜癌細胞 Ishikawa

貨物編碼

BFN60805245

產品規格

T25培養瓶x1

1.5ml凍存管x2

細胞數量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研           1類

培養體系

DMEM高糖+10%FBS+1%雙抗

培養溫度

37℃

二氧化碳濃度

5%

簡介

人子宮內膜癌細胞 Ishikawa細胞來源于39歲患有子宮內膜腺癌的女性，表達ER、PR。有報道稱該細胞可產生促腎上腺皮質激素釋放激素，胎盤堿性磷酸酶、絨膜促性腺激素.該細胞引種自ECACC

注釋

Part of: ENCODE project common cell types; tier 3.

Doubling time: 36 hours (at 9th passage), 29 hours (at 40th passage), 27 hours (at 50th passage) (DOI=10.1007/978-4-431-53981-0_2); 35.14 +- 2.68 hours (PubMed=23255909).

Omics: Array-based CGH.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

Misspelling: Ischikawaa; Occasionally.

STR信息

Amelogenin        X

CSF1PO        11,12

D2S1338        20

D3S1358        15,17

D5S818        10,11

D7S820        9,10

D8S1179        12,16

D13S317        9,12

D16S539        9

D18S51        13,19

D19S433        12.2,14

D21S11        28

FGA        21

Penta D        10,11

Penta E        11,19

TH01        9,10

TPOX        8

vWA        14,17

參考文獻

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017

Korch C., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.

DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.

Gynecol. Oncol. 127:241-248(2012)

PubMed=23255909; DOI=10.3892/ol.2012.975

Zhao S.-Z., Li G.-X., Yang L., Li L., Li H.-Y.

Response-specific progestin resistance in a newly characterized Ishikawa human endometrial cancer subcell line resulting from long-term exposure to medroxyprogesterone acetate.

Oncol. Lett. 5:139-144(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017

Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

A landscape of pharmacogenomic interactions in cancer.

Cell 166:740-754(2016)